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1996-03-04
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Document 0587
DOCN M9640587
TI [Adult HTLV-I positive leukemia-lymphoma in Argentina]
DT 9604
AU Gioseffi ON; Nucifora E; Fantl D; Dufour C; Milone J; Di Paolo H;
Hospital Nacional Profesor Alejandro Posadas, Prov. de Buenos; Aires,
Argentina.
SO Sangre (Barc). 1995 Oct;40(5):421-4. Unique Identifier : AIDSLINE
MED/96151813
AB Human T-cell lymphotropic virus type I (HTLV-I) is associated with adult
T-cell leukaemia/lymphoma (ATLL) and tropical spastic paraparesis
(TSP/HAM) in endemic and non-endemic areas. Serological studies have
shown that HTLV-I is prevalent in some Latin American countries such as
Brasil, Chile, Colombia, Peru and Uruguay. We describe here the clinical
and laboratory features of five cases of ATLL diagnosed in Argentina.
All patients (4 males, 1 female; median age 48.2 years) were of
caucasian origin; 4 born in Argentina and 1 in Chile. High risk factors
for HTLV-I infection were not apparent in Argentina patients, whereas
the Chilean resident, who was a promiscuous heterosexual, travelled
through Chile frequently. Positive results for antibodies to HTLV-I were
detected in all five cases and in some of their relatives. This report
suggests that HTLV-I infection may be endemic in, Argentina where TSP
has also been described.
DE Adult Argentina/EPIDEMIOLOGY English Abstract Female Human
HTLV-I/*IMMUNOLOGY Leukemia-Lymphoma, T-Cell, Acute,
HTLV-I-Associated/*EPIDEMIOLOGY/ VIROLOGY Male Middle Age JOURNAL
ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).